The highly anticipated Ramble Hotel has opened its doors at 25th and Larimer streets in River North.

The Ramble is the first hotel in Denver’s industrial and artistic RiNo neighborhood. Death & Co. is the lobby bar for the 50-room boutique hotel, which also has a café bar serving breakfast and lunch; Suite 6A, a reservation-only private bar featuring a cocktail tasting menu experience; and The Garden, a courtyard bar. All of the establishments are operated by Death & Co., an award-winning New York City cocktail bar that chose Denver for its second outpost. Death & Co. will open Friday.

The Ramble also is home to Vauxhall, an intimate music venue, theater and bar, and Super Mega Bien, an independent pan-Latin restaurant from James Beard-nominated chef Dana Rodriguez.

Designed by Denver-based architecture and interior design firm Johnson Nathan Strohe, the hotel’s design is inspired by 17th-century French salons, which served as platforms for exchanging ideas and creating a sense of community. Spaces inside The Ramble are intended to foster conversations, engagement and interaction among guests.

“Authentic design and materials are at the forefront of The Ramble Hotel,” Johnson Nathan Strohe partner Tobias Strohe said. “Inspired by Old World charm and influenced by traditional salons, our design for this project reflects owner Ryan Diggins’ true adherence to detail and craftsmanship — two principles that have made RiNo a hub for artists and creatives for decades. The edifice is designed to engage the passerby, the hotel guest and the restaurant patron alike.”

The Ramble balances RiNo’s industrial nature and au courant style by using materials that are traditional and of lasting quality but with an avant-garde look fitting for a modern boutique hospitality experience, Strohe said. The design is reminiscent of the historic warehouse buildings found throughout RiNo and the Lower Downtown neighborhoods. The Ramble features factory pane glazing and red-orange brick. There is a steel storefront and building base incorporated at the ground level.

“Each aspect of the design involved extensive research of historic buildings in RiNo and LoDo," Strohe said. “We worked alongside local masons to ensure accuracy in the brick details.”